H2N2V1, 1957, Analysis, bibRecord, 000216

[Hemagglutinin antigenic determinants of influenza viruses H1N1 isolated 1953-1957 in the composition of the hemagglutinins of influenza viruses H1N1 isolated 1978-1979].

Identifieur interne : 000216 ( 1957/Analysis ); précédent : 000215; suivant : 000217

[Hemagglutinin antigenic determinants of influenza viruses H1N1 isolated 1953-1957 in the composition of the hemagglutinins of influenza viruses H1N1 isolated 1978-1979].

Auteurs : E I Isaeva ; Z I Rovnova ; A L Platonova ; T S Belkina ; P N Kosiakov

Source :

Voprosy virusologii [ 0507-4088 ]

RBID : pubmed:6176070

Descripteurs français

KwdFr :
- Adsorption, Animaux, Anticorps antiviraux (analyse), Anticorps hétérophiles (analyse), Chromatographie sur gel, Facteurs temps, Hémagglutinines virales (analyse), Lapins, Sous-type H1N1 du virus de la grippe A, Sérums immuns (immunologie), Virus de la grippe A (immunologie), Épitopes (analyse).
MESH :
- analyse : Anticorps antiviraux, Anticorps hétérophiles, Hémagglutinines virales, Épitopes.
- immunologie : Sérums immuns, Virus de la grippe A.
- Adsorption, Animaux, Chromatographie sur gel, Facteurs temps, Lapins, Sous-type H1N1 du virus de la grippe A.

English descriptors

KwdEn :
- Adsorption, Animals, Antibodies, Heterophile (analysis), Antibodies, Viral (analysis), Chromatography, Gel, Epitopes (analysis), Hemagglutinins, Viral (analysis), Immune Sera (immunology), Influenza A Virus, H1N1 Subtype, Influenza A virus (immunology), Rabbits, Time Factors.
MESH :
- chemical , analysis : Antibodies, Heterophile, Antibodies, Viral, Epitopes, Hemagglutinins, Viral.
- chemical , immunology : Immune Sera.
- immunology : Influenza A virus.
- Adsorption, Animals, Chromatography, Gel, Influenza A Virus, H1N1 Subtype, Rabbits, Time Factors.

Abstract

Immunological analysis of antigenic determinants in the composition of hemagglutinins (HA) of H1N1 viruses isolated in the epidemic season of 1978-1979 showed their difference from A/USSR/090/77 virus HA. The A/Brazil/11/78 HA is characterized by 3 antigenic determinants two of which are identical with those of A/USSR/090/77 HA and one shows relationship with HA determinant of A/Omachi/1/53 virus, A/Fukushima/103/78 and A/Kagoshima/22/79 HAs are characterized by 1 determinant common with that of A/USSR/090/77 HA and 2 determinants identical with A/Omachi/1/53 virus HA. HAs of these viruses contain a determinant responsible for the antigenic relation of A/Omahi/1/53 HA with that of H1N1 viruses isolated in 1956-1957. The results suggest that the antigenic drift of HA of H1N1 viruses isolated in 1977-1979 occurs by the cycle characteristic of HA of H1N1 viruses isolated in 1950-1957. By the sensitivity to alpha-, beta-, and gamma-inhibitory of rabbit serum H1N1 viruses isolated in 1947-1957 and in 1977-1979 are quite similar with the exception of A/USSR/184/79 virus showing high sensitivity to gamma-inhibitors like H2N2 and H2N2 viruses.

PubMed: 6176070

Affiliations:

Links to Exploration step

pubmed:6176070

Le document en format XML

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<term>Chromatography, Gel</term>
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<term>Hemagglutinins, Viral (analysis)</term>
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<term>Chromatographie sur gel</term>
<term>Facteurs temps</term>
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<term>Lapins</term>
<term>Sous-type H1N1 du virus de la grippe A</term>
<term>Sérums immuns (immunologie)</term>
<term>Virus de la grippe A (immunologie)</term>
<term>Épitopes (analyse)</term>
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<term>Chromatography, Gel</term>
<term>Influenza A Virus, H1N1 Subtype</term>
<term>Rabbits</term>
<term>Time Factors</term>
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<term>Animaux</term>
<term>Chromatographie sur gel</term>
<term>Facteurs temps</term>
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<front><div type="abstract" xml:lang="en">Immunological analysis of antigenic determinants in the composition of hemagglutinins (HA) of H1N1 viruses isolated in the epidemic season of 1978-1979 showed their difference from A/USSR/090/77 virus HA. The A/Brazil/11/78 HA is characterized by 3 antigenic determinants two of which are identical with those of A/USSR/090/77 HA and one shows relationship with HA determinant of A/Omachi/1/53 virus, A/Fukushima/103/78 and A/Kagoshima/22/79 HAs are characterized by 1 determinant common with that of A/USSR/090/77 HA and 2 determinants identical with A/Omachi/1/53 virus HA. HAs of these viruses contain a determinant responsible for the antigenic relation of A/Omahi/1/53 HA with that of H1N1 viruses isolated in 1956-1957. The results suggest that the antigenic drift of HA of H1N1 viruses isolated in 1977-1979 occurs by the cycle characteristic of HA of H1N1 viruses isolated in 1950-1957. By the sensitivity to alpha-, beta-, and gamma-inhibitory of rabbit serum H1N1 viruses isolated in 1947-1957 and in 1977-1979 are quite similar with the exception of A/USSR/184/79 virus showing high sensitivity to gamma-inhibitors like H2N2 and H2N2 viruses.</div>
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[Hemagglutinin antigenic determinants of influenza viruses H1N1 isolated 1953-1957 in the composition of the hemagglutinins of influenza viruses H1N1 isolated 1978-1979].

[Hemagglutinin antigenic determinants of influenza viruses H1N1 isolated 1953-1957 in the composition of the hemagglutinins of influenza viruses H1N1 isolated 1978-1979].

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

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Pour manipuler ce document sous Unix (Dilib)

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